NOT KNOWN FACTUAL STATEMENTS ABOUT NEMBUTAL EFFECTS

pentobarbital will lower the level or impact of pitolisant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Closely. Pitolisant exposure is reduced by 50% if coadministered with solid CYP3A4 inducers.Contraindicated (1)pentobarbital will reduce the level or effect of lumacaftor/ivacaftor by affecting hepatic/i